Early-stage research exploration

Biology is complex.
Intelligence finds
the patterns.

An emerging collaboration between biomedical researchers and AI systems engineering, exploring longitudinal health data, early disease signals, and computational biology.

Meet the research collaborators
Connecting evidence across biological scalesA conceptual map connects longitudinal observations, genomic context, and research literature to a shared research question. It does not represent patient data or findings.Longitudinal observationsGenomic contextResearch literatureResearch questionEvidence connected
Conceptual research architecture / no patient data
An exploratory initiative. Institutional affiliations are provided for identification and do not imply institutional endorsement.
Our research question

What becomes visible
when evidence connects?

Biological signals rarely arrive in one place. They emerge across molecular measurements, observations over time, and a growing body of scientific literature.

We are exploring how an evidence-connected intelligence system could help researchers connect these layers, frame testable hypotheses, and investigate the biological context behind a signal.

The work is at the stage of defining research questions and possible collaborations. No clinical performance or validated disease-detection capability is claimed.

Research collaborators

Different disciplines.
A shared line of inquiry.

Biological interpretation, genomic context, and the engineering to bring evidence together.

Gang Huang

Hematology & translational biology

Gang Huang Ph.D.

Professor · Kathryn Mays Johnson Distinguished Chair in Oncology, UT Health San Antonio

Studies blood cancers, mitochondrial metabolism, and tumor immunology, with an emphasis on translating biological mechanisms into therapeutic approaches.

His work includes MDS disease models and cell-based approaches to solid tumors. He also founded Powerhouse Therapeutics to advance laboratory inventions toward application.

Yu Luan

Genomics & epigenetics

Yu Luan Ph.D.

Assistant Professor · Cell Systems & Anatomy, UT Health San Antonio

Investigates how genetic variation, epigenetic regulation, and 3D genome organization influence cell identity, disease, and therapeutic response.

Combines functional genomics with computational modeling. Recognition includes the 2024 CPRIT Scholar and UT System Rising STARs awards.

Deheng Sun

AI systems engineering

Deheng Sun

Founder & CEO · Flow Mind AI Inc. / Principal Software Engineer · Palo Alto Networks

AI systems builder with 11+ years of experience in enterprise backend, platform, and LLM-powered systems. A Principal Software Engineer at Palo Alto Networks and founder of Flow Mind, the company behind Mad Dog Alpha.

Takes AI systems from prototype to production, combining distributed systems, API design, and cloud-native infrastructure with RAG, context engineering, and LLM orchestration. Builds evaluation pipelines, regression checks, guardrails, and observability to make AI workflows reliable and maintainable at enterprise scale.

Areas of exploration

From scattered signals
to researchable questions.

Signals across time

Explore how longitudinal observations could reveal patterns that isolated measurements miss.

Biological context

Connect candidate signals with gene regulation, cell states, and disease mechanisms.

Traceable intelligence

Keep source evidence and uncertainty visible as researchers develop and evaluate hypotheses.

Scientific foundations

Selected research & recognition.

Prior academic work and awards of individual collaborators, providing context for this exploration.

Nature / 2024

Deciphering the impact of genomic variation on function.

Briefings in Bioinformatics / 2024

scENCORE: predicting chromatin conformation from single-cell epigenetic data.

Huang Lab / Research

Mitochondrial metabolism, myeloid malignancies, and translational cancer research.

Yu Luan CPRIT Scholar Award · UT System Rising STARs Award, 2024

View faculty record

Biomedical Research Initiative

A conversation is
a good place to start.

For research collaboration, early-stage investment conversations, or an introduction to the initiative, get in touch with Deheng.

Discuss the initiative

Early-stage research exploration. Institutional affiliations do not imply institutional endorsement.